Participación de las proteínas Com_YlbF en la modulación de la virulencia mediada por vesículas en Staphylococcus aureus

Datos básicos

Proyecto de investigación interno Nacional PCI-2024-0020 Año de incio: 2024 Año de finalización: 2026

Objetivos del proyecto

Establecer el rol de las proteínas Com_YlbF (Qrp/YheA, YlbF y YmcA) en la generación y composición de las vesículas extracelulares de membrana de Staphylococcus aureus y su correlación con la modulación de la virulencia en eritrocitos.

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Unidades de investigación

Outputs del proyecto


A protocol for loading Calcein-AM into extracellular vesicles from mammalian cells for clear visualization with a fluorescence microscope coupled to a deconvolution system

Calderón-Peláez M.-A., Castellanos J.E., Velandia-Romero M.L.

Article. 10.1371/journal.pone.0317689. 2025

  • Open Access.

Bacteraemia and proinflammatory response after non-surgical periodontal therapy and adjunctive antibiotics in patients with recent acute coronary syndrome

LAFAURIE, GLORIA INES; (...); Mendoza F.

Article. 10.1016/j.diagmicrobio.2024.116662. 2025


Design and Evaluation of NSAID Derivatives as AKR1C3 Inhibitors for Breast Cancer Treatment through Computer-Aided Drug Design and In Vitro Analysis.

Fonseca-Benítez V; (...); Guevara-Pulido J

Article. 10.3390/molecules29081802. 2024


Design, synthesis, and in vitro evaluation of a carbamazepine derivative with antitumor potential in a model of Acute Lymphoblastic Leukemia

Álvarez-Gómez C., Fonseca-Benítez A.V., GUEVARA, JAMES OSWALDO

Article. 10.1371/journal.pone.0319415. 2025

  • Open Access.

Extracellular vesicles in ZIKV infection: Carriers and facilitators of viral pathogenesis?

CALDERON, MARIA ANGELICA, CASTELLANOS, JAIME EDUARDO, Velandia-Romero M.L.

Article. 10.1177/00368504241312073. 2025


Influence of age, sex, and presence of cleft lip and palate on the quantity and quality of saliva-derived DNA

VARGAS, LINA MARÍA; (...); González-Carrera M.C.

Article. 10.1016/j.jobcr.2025.01.030. 2025


Organocatalytic kinetic resolution of 1,5-dicarbonyl compounds through a retro-Michael reaction

GUEVARA, JAMES OSWALDO; (...); Pedrosa R.

Article. 10.3762/bjoc.21.34. 2025


Pathogenic and periodontal bacteria may contribute to the fatal outcome of critically ill elderly COVID-19 patients

Madroñero L.J.; (...); CASTELLANOS, JAIME EDUARDO

Article. 10.1038/s41598-025-88518-y. 2025


Periodontitis Progression During Cardiac Rehabilitation After Acute Coronary Syndrome: Cohort Study

Moscoso S.B.; (...); LAFAURIE, GLORIA INES

Article. 10.1111/odi.15382. 2025


Submucosal Microbiome Profiles in Paired and Unpaired Samples From Healthy and Peri-Implantitis Dental Implants

Tocarruncho O.I.; (...); LAFAURIE, GLORIA INES

Article. 10.1111/cid.13423. 2025


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