Confirmed cases of COVID-19 after vaccination against COVID in health personnel in Bogotá, Colombia

Autores organización

• Alexandra Porras Ramirez

  Autor

• Rafael Antonio Sanchez Paris

  Autor

Autores

• López-Devia W
• Moreno-Perilla Z
• Jurado-Zambrano R
• Luna-Jaspe Caina C
• Sefair C
• Ramos N
• Otero-Cadena M
• Lievano R

Grupos de investigación

• Grupo de Inmunología celular y molecular Universidad El Bosque (InmuBo)

  Investigador

  Maria Consuelo Romero Sanchez

• Medicina Comunitaria y Salud Colectiva

Resumen

Objective: The present study aims to estimate the frequency of COVID 19 infections in vaccinated health personnel at a Los CObos Medical Center in Bogotá, Colombia. The percentage of people positive to the PCR test and their clinical characteristics were analyzed. Methods: We performed a cross-sectional study. The primary study variable was the COVID vaccination registry. We analyzed sex, age, signs, and symptoms. Multivariable logistic regression was applied to assess changes over time and to identify variables associated with vaccination in target groups. Results: A cohort of 999 people working at Los Cobos Medical Center and followed from March to August 2021. The average age of this cohort was 37.0 years (devest = 10.5 years), 67.7 % were women. Two hundred eleven physicians, 287 nurses, 305 assistants, and 196 clerks follows. In addition, 8.4 % to be PCR positive after vaccination. The average age was 36.0 (devest = 23.4 years), 59 women and 25 men. Of these, 15 were administrative, 14 were doctors, 29 nurses, and 26 nursing assistants. The vaccination status found that 21.4 % do not vaccinates, 7.1 % were partially vaccinated, and 71.4 % with a complete schedule. When questioned about symptoms in these patients, 4.0 % were symptomatic, and 5.9 % were asymptomatic. Conclusions: A recent epidemiological study involving 12,364 health workers with a mean age of 38 years quantifies the protection in six months from the vaccine. The presence of antibodies was associated with 83 % protection against active SARS-CoV-2 infection (PCR positivity during the study period), which confirms the existence of protective Immunity at levels comparable to those obtained by the approved vaccines; our study found effectiveness of 92.6 %. Higher than that found in this study, possibly explained by the characteristics of the individuals included. © 2023

Copyright © 2023. Published by Elsevier Ltd.

Keywords

• Adult; Colombia; COVID-19; Cross-Sectional Studies; Female; Health Personnel; Humans; Male; SARS-CoV-2; Vaccination; SARS-CoV-2 antibody; adult; age; Article; clinical feature; cohort analysis; Colombia; controlled study; coronavirus disease 2019; cross-sectional study; disease duration; drug efficacy; epidemiological data; female; gender; health care personnel; human; major clinical study; male; nonhuman; nurse; nursing assistant; physician; polymerase chain reaction; quantitative analysis; Severe acute respiratory syndrome coronavirus 2; symptom assessment; vaccination; virus immunity; coronavirus disease 2019; health care personnel; vaccination