Portal de investigación
A New Generation of Vaccines in the Age of Immunotherapy
Fecha de publicación:
Fecha Ahead of Print:
Autores organización
Autores
- Addeo A
- Friedlaender A
- Giovannetti E
- Russo A
- de Miguel-Perez D
- Arrieta O
- Rolfo C
Grupos de investigación
Resumen
Purpose of review: Cancer vaccines are one of the most extensively studied immunotherapy type in solid tumors. Despite favorable presuppositions, so far, the use of cancer vaccines has been associated with disappointing results. However, a new generation of vaccines has been developed, promising to revolutionize the immunotherapy field. Recent findings: In this review, we aim to highlight the advances in cancer vaccines and the remaining hurdles to overcome. Summary: Cancer vaccination has experienced tremendous progress in the last decade, with myriad promising developments. Future efforts should focus on optimization of target identification, streamlining of most appropriate vaccination strategies, and adjuvant development, as well as predictive biomarker identification. Cautious optimism is warranted in the face of early successes seen in recent clinical trials for oncolytic vaccines. If an approach were to prove successful, it could revolutionize cancer therapy the way ICIs did in the previous decade. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Datos de la publicación
- ISSN/ISSNe:
- 1523-3790, 1534-6269
- Tipo:
- Review
- Páginas:
- 137-137
- Enlace a otro recurso:
- www.scopus.com
Current Oncology Reports Springer
Citas Recibidas en Web of Science: 8
Citas Recibidas en Scopus: 13
Documentos
- No hay documentos
Filiaciones
Keywords
- Antigens, Neoplasm; Cancer Vaccines; Humans; Immunotherapy; Neoplasms; cancer vaccine; DNA vaccine; peptide vaccine; RNA vaccine; virus antigen; cancer vaccine; tumor antigen; age; cancer immunization; cancer immunotherapy; clinical effectiveness; human; immune response; immunostimulation; Review; risk factor; survival rate; tumor microenvironment; vaccine immunogenicity; immunology; immunotherapy; neoplasm; procedures
Proyectos asociados
Determinación de la huella transcipcional de mastocitos aislados de pulpa dental humana sana y con signos clínicos de inflamación
Investigador Principal: MARIA ROSA BUENAHORA TOBAR
PCI-2019-10765 . 2020
EFECTO DEL EXTRACTO DE Trametes versicolor SOBRE EL FENOTIPO Y LA FUNCIÓN DE CÉLULAS DENDRÍTICAS HUMANAS CONDICIONADAS CON MEDIOS DE CÉLULAS DE CARCINOMA ORAL
Investigador Principal: ANDRES FELIPE CARDONA MENDOZA
PCI-2019-10805 . 2020
Citar la publicación
Addeo A,Friedlaender A,Giovannetti E,Russo A,de Miguel D,Arrieta O,Cardona AF,Rolfo C. A New Generation of Vaccines in the Age of Immunotherapy. Curr Oncol Rep. 2021. 23(12):p. 137-137. IF:5,945. (2).