Update on the epidemiology of carbapenemases in Latin America and the Caribbean
Autores organización
Autores
- Appel, TM
- Esparza, G
- Gales, AC
- Levy-Hara, G
- Cornistein, W
- Vega, S
- Nuñez, D
- Cuellar, L
- Bavestrello, L
- Castañeda-Méndez, PF
- Villalobos-Vindas, JM
Grupos de investigación
Resumen
Introduction Carbapenemases are beta-lactamases able to hydrolyze a wide range of beta-lactam antibiotics, including carbapenems. Carbapenemase production inEnterobacterales, Pseudomonas aeruginosa,andAcinetobacterspp., with and without the co-expression of other beta-lactamases is a serious public health threat. Carbapenemases belong to three main classes according to the Ambler classification: class A, class B, and class D. Areas covered Carbapenemase-bearing pathogens are endemic in Latin America. In this review, we update the status of carbapenemases in Latin America and the Caribbean. Expert opinion Understanding the current epidemiology of carbapenemases in Latin America and the Caribbean is of critical importance to improve infection control policies limiting the dissemination of multi-drug-resistant pathogens and in implementing appropriate antimicrobial therapy.
Datos de la publicación
- ISSN/ISSNe:
- 1478-7210, 1744-8336
- Tipo:
- Review
- Páginas:
- 197-213
- Enlace a otro recurso:
- www.scopus.com
Expert Review Of Anti-Infective Therapy TAYLOR & FRANCIS LTD
Citas Recibidas en Web of Science: 41
Citas Recibidas en Scopus: 69
Documentos
- No hay documentos
Filiaciones
Keywords
- Acinetobacter baumannii; carbapenemases; carbapenems; carbapenem resistance; carbapenem-resistantEnterobacterales(CRE); Klebsiella pneumoniae; Latin America; Pseudomonas aeruginosa
Proyectos asociados
Caracterización de los mecanismos de resistencia en aislamientos clínicos de enterobacterias resistentes a ceftazidime/avibactam recolectados en 13 instituciones de salud entre 2016 y 2017.
Investigador Principal: MARIA FERNANDA MOJICA MEDINA
PCI-2019-10808 . 2020
Creating a Latin America network for clinical training and support of pharmacists and hospital financial decision makers involved in ASPs
Investigador Principal: MARIA VIRGINIA VILLEGAS BOTERO
UEB-2020-585 . 2020
Citar la publicación
García JC,Appel TM,Esparza G,Gales AC,Levy G,Cornistein W,Vega S,Nuñez D,Cuellar L,Bavestrello L,Castañeda PF,Villalobos JM,Villegas MV. Update on the epidemiology of carbapenemases in Latin America and the Caribbean. Expert Rev Anti Infect Ther. 2021. 19(2):p. 197-213. IF:5,854. (1).