Update on the epidemiology of carbapenemases in Latin America and the Caribbean

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Autores organización

Autores

  • Appel, TM
  • Esparza, G
  • Gales, AC
  • Levy-Hara, G
  • Cornistein, W
  • Vega, S
  • Nuñez, D
  • Cuellar, L
  • Bavestrello, L
  • Castañeda-Méndez, PF
  • Villalobos-Vindas, JM

Grupos de investigación

Resumen

Introduction Carbapenemases are beta-lactamases able to hydrolyze a wide range of beta-lactam antibiotics, including carbapenems. Carbapenemase production inEnterobacterales, Pseudomonas aeruginosa,andAcinetobacterspp., with and without the co-expression of other beta-lactamases is a serious public health threat. Carbapenemases belong to three main classes according to the Ambler classification: class A, class B, and class D. Areas covered Carbapenemase-bearing pathogens are endemic in Latin America. In this review, we update the status of carbapenemases in Latin America and the Caribbean. Expert opinion Understanding the current epidemiology of carbapenemases in Latin America and the Caribbean is of critical importance to improve infection control policies limiting the dissemination of multi-drug-resistant pathogens and in implementing appropriate antimicrobial therapy.

Datos de la publicación

ISSN/ISSNe:
1478-7210, 1744-8336

Expert Review Of Anti-Infective Therapy  TAYLOR & FRANCIS LTD

Tipo:
Review
Páginas:
197-213
Enlace a otro recurso:
www.scopus.com

Citas Recibidas en Web of Science: 41

Citas Recibidas en Scopus: 69

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Keywords

  • Acinetobacter baumannii; carbapenemases; carbapenems; carbapenem resistance; carbapenem-resistantEnterobacterales(CRE); Klebsiella pneumoniae; Latin America; Pseudomonas aeruginosa

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