Uterine Artery Pulsatility Index as a Pre-eclampsia Predictor in the 3 Trimesters in Women with Singleton Pregnancies

Autores organización

• Alexandra Porras Ramirez

  Autor

• Ximena Carolina Romero Infante

  Autor

Autores

• Guzmán, YN
• Uriel, M

Grupos de investigación

• Grupo de Inmunología celular y molecular Universidad El Bosque (InmuBo)

  Investigador

  Maria Consuelo Romero Sanchez

• Grupo de Investigación Medicina Materno Fetal y Ginecología - El Bosque MMFG-EB

  Investigador

  Ximena Carolina Romero Infante

Resumen

Objective To evaluate the mean uterine artery pulsatility index (UtAPI) in each trimester of pregnancy as a predictor of early or late pre-eclampsia (PE) in Colombian pregnant women. Methods The UtAPI was measured in singleton pregnancies in each trimester. Uterine artery pulsatility index as predictor of PE was evaluated by odds ratio (OR), receiver operating characteristic (ROC) curves, and Kaplan-Meier diagram. Results Analysis in the 1 (st) and 3 (rd) trimester showed that abnormal UtAPI was associated with early PE (OR: 5.99: 95% confidence interval [CI]: 1.64-21.13; and OR: 10.32; 95%CI: 2.75-42.49, respectively). Sensitivity and specificity were 71.4 and 79.6%, respectively, for developing PE (area under the curve [AUC]: 0.922). The Kaplan-Meier curve showed that a UtAPI of 0.76 (95%CI: 0.58-1.0) in the 1 (st) trimester was associated with early PE, and a UtAPI of 0.73 (95%CI: 0.55-0.97) in the 3 (rd) trimester was associated with late PE. Conclusion Uterine arteries proved to be a useful predictor tool in the 1 (st) and 3 (rd) trimesters for early PE and in the 3 (rd) trimester for late PE in a pregnant population with high prevalence of PE.

Federação Brasileira de Ginecologia e Obstetrícia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

Keywords

• uterine artery doppler; preeclampsia; pregnancy; perinatal care; screening