Portal de investigación
Antimicrobial Stewardship programs in Peru: A fundamental agreement
Fecha de publicación:
Autores organización
Autores
- Hernández-Gómez, C
- Hercilla, L
- Mendo, F
- Pérez-Lazo, G
- Contreras, E
- Ramírez, E
- Flores, W
- Julca, A
- Chuquiray, N
- Arenas, B
- Abarca, S
- Viñas, M
- Linares, E
- Illescas, LR
Grupos de investigación
Resumen
Background. Antimicrobial resistance (AMR) is a global threat to public health. Antibiotic stewardship programs (AMSP) promote the proper use of antimicrobials, improve clinical and economic outcomes, and helps containing the AMR. Aim: To evaluate the diagnostic phase of the AMS programs and early implementation of AMS at three high complexity hospitals that belong to the social security system in Peru. Methods: A quasi-experimental multicenter study was implemented. The construction of the AMSP, microbiological baselines, antimicrobial consumption and consensus on AMS activities were evaluated at the diagnosis and early implementation periods of the AMSP Results: Following implementation, hospitals doubled their score of resources and processes available for the AMS program from 6.75 to 13.75. The prevalence of extended spectrum beta-lactamase producing enterobacteria was 50-60% while Pseudomonas aeruginosa averaged 69% resistance to carbapenems. The defined daily dose (DDD) of ceftriaxone was 13.63, vancomycin 7.35 and meropenem 6.73 in average. Hospitals A and C decreased the use of antimicrobials (30-50%). Discussion: The implementation of the AMSP in the three hospitals was achieved through diverse strategies designed by multidisciplinary teams, which in addition to its articulation, reduce the consumption of broad spectrum antimicrobials at an early stage.
Datos de la publicación
- ISSN/ISSNe:
- 0716-1018, 0717-6341
- Tipo:
- Article
- Páginas:
- 565-575
Revista Chilena De Infectologia SOC CHILENA INFECTOLOGIA
Citas Recibidas en Web of Science: 9
Citas Recibidas en Scopus: 11
Documentos
- No hay documentos
Filiaciones
Keywords
- Antimicrobial stewardship; drug resistance; multiple; consensus
Proyectos asociados
Citar la publicación
Hernández C,Hercilla L,Mendo F,Pérez G,Contreras E,Ramírez E,Flores W,Julca A,Chuquiray N,Arenas B,Abarca S,Viñas M,Linares E,Villegas MV,Illescas LR. Antimicrobial Stewardship programs in Peru: A fundamental agreement. Rev Chilena Infectol. 2019. 36. (5):p. 565-575. IF:0,520. (4).