Portal de investigación
Desarrollo y validación de un kit de diagnóstico molecular y pronóstico por serología para dengue en Colombia
Datos básicos
Objetivos del proyecto
Producir y validar un sistema económico y rápido de detección de RNA de DENV y un sistema de detección de biomarcadores mastocitarios producidos durante la infección que faciliten el diagnóstico molecular y la evaluación del pronóstico de la enfermedad en población pediátrica de Cartagena.
Documentos
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Unidades de investigación
Outputs del proyecto
A protocol for loading Calcein-AM into extracellular vesicles from mammalian cells for clear visualization with a fluorescence microscope coupled to a deconvolution system
Calderón-Peláez M.-A., Castellanos J.E., Velandia-Romero M.L.
Article. 10.1371/journal.pone.0317689. 2025
A tangled threesome: understanding arbovirus infection in Aedes spp. and the effect of the mosquito microbiota.
Mantilla-Granados JS, Castellanos JE, Velandia-Romero ML
Article. 10.3389/fmicb.2023.1287519. 2024
Association of Root Biofilm Bacteriome with Root Caries Lesion Severity and Activity.
Usuga-Vacca M; (...); Martignon S
Article. 10.1159/000535923. 2024
Clinical and Epidemiological Characteristics of Arbovirus Infections in Blood Donors
Cáceres, A; (...); Delgado, F
Meeting Abstract. 10.1111/trf.127_17554. 2023
Cost of dengue in Colombia: A systematic review
Rodríguez-Morales A.J.; (...); Fuquen M.
Article. 10.1371/journal.pntd.0012718. 2024
Cyclooxygenase upregulation in cytomegalovirus-infected gingival fibroblasts: Implications for periodontal disease
Delgadillo-Barrera S.; (...); CASTELLANOS, JAIME EDUARDO
Article. 10.1016/j.ajoms.2024.07.004. 2025
Development and Optimization of a Multiplex Real-Time RT-PCR to Detect SARS-CoV-2 in Human Samples
CORONEL, CAROLINA; (...); Fonseca-Benitez A.
Article. 10.1155/2024/4894004. 2024
Environmental and anthropic factors influencing Aedes aegypti and Aedes albopictus (Diptera: Culicidae), with emphasis on natural infection and dissemination: Implications for an emerging vector in Colombia
Mantilla-Granados J.S.; (...); CASTELLANOS, JAIME EDUARDO
Article. 10.1371/journal.pntd.0012605. 2025
Extracellular vesicles in ZIKV infection: Carriers and facilitators of viral pathogenesis?
CALDERON, MARIA ANGELICA, CASTELLANOS, JAIME EDUARDO, Velandia-Romero M.L.
Article. 10.1177/00368504241312073. 2025
Gut expression of CD71 and co-localisation with Dec-1 associated with high levels of serum SIgA and disease activity in SpA
DE AVILA, JULIETTE; (...); ROMERO, MARIA CONSUELO
Article. 10.1038/s41598-025-03532-4. 2025
High prevalence of dengue, Zika, and chikungunya viruses in blood donors during a dengue outbreak and an endemic period in Colombia
Cáceres Munar B.A.; (...); CASTELLANOS, JAIME EDUARDO
Article. 10.3389/fmed.2024.1380129. 2024
Modulation of TRPV1 on Odontoblast-like Cells Using Capsazepine-Loaded Nanogels
Bernal-Cepeda L.J.; (...); CASTELLANOS, JAIME EDUARDO
Article. 10.3390/pharmaceutics16030355. 2024
Pathogenic and periodontal bacteria may contribute to the fatal outcome of critically ill elderly COVID-19 patients
Madroñero L.J.; (...); CASTELLANOS, JAIME EDUARDO
Article. 10.1038/s41598-025-88518-y. 2025
Proteome of the 2-h in vivo Formed Acquired Enamel Pellicle of Adolescents with Erosive Tooth Wear, Caries, or Sound
AVILA, LEIDY VIVIANA; (...); MARTIGNON, STEFANIA
Article. 10.1159/000541026. 2025
Seroprevalence, infection, and personal protective equipment use among Colombian healthcare workers during the COVID-19 pandemic
Beltrán EO; (...); Castellanos JE
Article. 10.3389/fpubh.2023.1225037. 2023
Simultaneous Detection of Dengue, Zika and Chikungunya Viruses in Blood Donors During Two Different Epidemiological Periods in Colombia
Cáceres, A; (...); Delgado, F
Meeting Abstract. 10.1111/trf.174_17554. 2023
Small extracellular vesicles from the human endothelial cell line EA.hy 926 exert a self-cell activation and modulate DENV-2 genome replication and infection in naïve endothelial cells
Calderón-Peláez M.-A.; (...); VELANDIA, MYRIAM LUCIA
Article. 10.1371/journal.pone.0310735. 2024
The Epidemiological Impact of Dengue in Colombia: A Systematic Review
Rodriguez-Morales A.J.; (...); Fuquen M.
Article. 10.4269/ajtmh.23-0907. 2025
Zika Virus: A Neurotropic Warrior against High-Grade Gliomas—Unveiling Its Potential for Oncolytic Virotherapy
Calderón-Peláez M.-A.; (...); VELANDIA, MYRIAM LUCIA
Article. 10.3390/v16040561. 2024
Campos de Estudio
Citar el proyecto
Desarrollo y validación de un kit de diagnóstico molecular y pronóstico por serología para dengue en Colombia. (UEB-2022-705). 2023-2026. IP:JAIME EDUARDO CASTELLANOS PARRA.