Desarrollo de un sistema de detección de virus causantes de infección respiratoria por RT-qPCR: desde la producción de enzimas hasta la validación en laboratorio

Datos básicos

Proyecto de investigación interno Nacional PCI-2023-0035 Año de incio: 2023 Año de finalización: 2025

Objetivos del proyecto

Fortalecer la gobernanza ambiental del valle de Paipa, a partir de la evaluación y conocimiento de los servicios ecosistémicos (S.E.), su estado y dinámica espacial con participación comunitaria, desde el enfoque del metabolismo socioecológico.

Documentos

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Participantes

Unidades de investigación

Outputs del proyecto


A Comparison of Lymphoid and Myeloid Cells Derived from Human Hematopoietic Stem Cells Xenografted into NOD-Derived Mouse Strains

Gutierrez-Barbosa H; (...); Chua JV

Article. 10.3390/microorganisms11061548. 2023

  • Open Access.

A protocol for loading Calcein-AM into extracellular vesicles from mammalian cells for clear visualization with a fluorescence microscope coupled to a deconvolution system

Calderón-Peláez M.-A., Castellanos J.E., Velandia-Romero M.L.

Article. 10.1371/journal.pone.0317689. 2025

  • Open Access.

A strategy for entomo-virological surveillance of yellow fever, dengue, zika, and chikungunya viruses in field-collected mosquitoes

Calderón-Peláez M.-A.; (...); Olano V.A.

Article. 10.1016/j.mex.2023.102356. 2023

  • Open Access.

A tangled threesome: understanding arbovirus infection in Aedes spp. and the effect of the mosquito microbiota.

Mantilla-Granados JS, Castellanos JE, Velandia-Romero ML

Article. 10.3389/fmicb.2023.1287519. 2024


Association of Root Biofilm Bacteriome with Root Caries Lesion Severity and Activity.

Usuga-Vacca M; (...); Martignon S

Article. 10.1159/000535923. 2024


Clinical and Epidemiological Characteristics of Arbovirus Infections in Blood Donors

Cáceres, A; (...); Delgado, F

Meeting Abstract. 10.1111/trf.127_17554. 2023


Cost of dengue in Colombia: A systematic review

Rodríguez-Morales A.J.; (...); Fuquen M.

Article. 10.1371/journal.pntd.0012718. 2024


Cyclooxygenase upregulation in cytomegalovirus-infected gingival fibroblasts: Implications for periodontal disease

Delgadillo-Barrera S.; (...); CASTELLANOS, JAIME EDUARDO

Article. 10.1016/j.ajoms.2024.07.004. 2025


Development and Optimization of a Multiplex Real-Time RT-PCR to Detect SARS-CoV-2 in Human Samples

CORONEL, CAROLINA; (...); Fonseca-Benitez A.

Article. 10.1155/2024/4894004. 2024


Environmental and anthropic factors influencing Aedes aegypti and Aedes albopictus (Diptera: Culicidae), with emphasis on natural infection and dissemination: Implications for an emerging vector in Colombia

Mantilla-Granados J.S.; (...); CASTELLANOS, JAIME EDUARDO

Article. 10.1371/journal.pntd.0012605. 2025


Extracellular vesicles in ZIKV infection: Carriers and facilitators of viral pathogenesis?

CALDERON, MARIA ANGELICA, CASTELLANOS, JAIME EDUARDO, Velandia-Romero M.L.

Article. 10.1177/00368504241312073. 2025


Gut expression of CD71 and co-localisation with Dec-1 associated with high levels of serum SIgA and disease activity in SpA

DE AVILA, JULIETTE; (...); ROMERO, MARIA CONSUELO

Article. 10.1038/s41598-025-03532-4. 2025


High prevalence of dengue, Zika, and chikungunya viruses in blood donors during a dengue outbreak and an endemic period in Colombia

Cáceres Munar B.A.; (...); CASTELLANOS, JAIME EDUARDO

Article. 10.3389/fmed.2024.1380129. 2024


Modulation of TRPV1 on Odontoblast-like Cells Using Capsazepine-Loaded Nanogels

Bernal-Cepeda L.J.; (...); CASTELLANOS, JAIME EDUARDO

Article. 10.3390/pharmaceutics16030355. 2024


Multisystem Failure in Fatal Dengue: Associations between the Infectious Viral Serotype and Clinical and Histopathological Findings

Rivera J; (...); Caldas ML

Article. 10.4269/ajtmh.22-0587. 2023


Pathogenic and periodontal bacteria may contribute to the fatal outcome of critically ill elderly COVID-19 patients

Madroñero L.J.; (...); CASTELLANOS, JAIME EDUARDO

Article. 10.1038/s41598-025-88518-y. 2025


Proteome of the 2-h in vivo Formed Acquired Enamel Pellicle of Adolescents with Erosive Tooth Wear, Caries, or Sound

AVILA, LEIDY VIVIANA; (...); MARTIGNON, STEFANIA

Article. 10.1159/000541026. 2025


Relaxin treatment stimulates the differentiation of mesenchymal stem cells into osteoblasts

Escobar LM; (...); Castellanos JE

Article. 10.1016/j.jds.2023.05.007. 2023

  • Open Access.

Seroprevalence, infection, and personal protective equipment use among Colombian healthcare workers during the COVID-19 pandemic

Beltrán EO; (...); Castellanos JE

Article. 10.3389/fpubh.2023.1225037. 2023

  • Open Access.

Simultaneous Detection of Dengue, Zika and Chikungunya Viruses in Blood Donors During Two Different Epidemiological Periods in Colombia

Cáceres, A; (...); Delgado, F

Meeting Abstract. 10.1111/trf.174_17554. 2023


Small extracellular vesicles from the human endothelial cell line EA.hy 926 exert a self-cell activation and modulate DENV-2 genome replication and infection in naïve endothelial cells

Calderón-Peláez M.-A.; (...); VELANDIA, MYRIAM LUCIA

Article. 10.1371/journal.pone.0310735. 2024

  • Open Access.

The Epidemiological Impact of Dengue in Colombia: A Systematic Review

Rodriguez-Morales A.J.; (...); Fuquen M.

Article. 10.4269/ajtmh.23-0907. 2025


The Interaction Effect of Anti-RgpA and Anti-PPAD Antibody Titers: An Indicator for Rheumatoid Arthritis Diagnosis

Castillo DM; (...); Castellanos JE

Article. 10.3390/jcm12083027. 2023

  • Open Access.

Tracing FX174 bacteriophage spreading during aerosol-generating procedures in a dental clinic

Beltrán EO; (...); Martignon S

Article. 10.1007/s00784-023-04937-z. 2023

  • Open Access.

Zika Virus: A Neurotropic Warrior against High-Grade Gliomas—Unveiling Its Potential for Oncolytic Virotherapy

Calderón-Peláez M.-A.; (...); VELANDIA, MYRIAM LUCIA

Article. 10.3390/v16040561. 2024


Análisis Del Riesgo En La Seguridad Transfusional Debido A La Circulación De Arbovirus En Colombia

Autor/es: Brian Alejandro Caceres Munar

Trabajo de grado de Maestría o Especialidad Médica

Director/es: CASTELLANOS, JAIME EDUARDO; DELGADO, FELIX GIOVANNI


Desarrollo De Un Algoritmo De Procesamiento De Imágenes Para La Cuantificación Preliminar De Contenido Intracelular De Polihidroxialcanoatos En Cultivos De Cupriavidus Necator

Trabajo de grado de pregrado

Director/es: MERCHAN, NURI ANDREA; AVENDAÑO, JONATHAN


Desarrollo De Un Dispositivo Portable De Visión Artificial Para La Identificación Y Cuantificación In Vitro De Cryptosporidium Spp. En Muestras De Agua

Trabajo de grado de pregrado

Director/es: MERCHAN, NURI ANDREA; AVENDAÑO, JONATHAN


Estrategia Para La Confirmación De Casos De Dengue, Su Clasificación Y Pronóstico: Aportes De Algunos Marcadores Serológicos Y Celulares

Autor/es: Carolina Coronel Ruiz

Tesis Doctoral

Director/es: VELANDIA, MYRIAM LUCIA; CASTELLANOS, JAIME EDUARDO


Evaluación De La Actividad Inmunomoduladora In Vitro De Un Aislado Clínico De Citomegalovirus Humano

Autor/es: Sonia Del Pilar Bohorquez Avila

Tesis Doctoral

Director/es: VELANDIA, MYRIAM LUCIA; CASTELLANOS, JAIME EDUARDO


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